TY - JOUR T1 - Implementation of Web-based High-Throughput Screening Calculation System AU - Cho, Seong-ho AU - Kim, Inhee AU - Kong, Jiwon AU - Kim, Daesan AU - Kwon, Namhoon AU - Burrier, Robert E. AU - Kim, Sunghoon JO - Journal of KIISE, JOK PY - 2019 DA - 2019/1/14 DO - 10.5626/JOK.2019.46.3.260 KW - high-throughput screening KW - luciferase assay KW - trust region reflective algorithm KW - non-linear regression analysis KW - data structuration AB - In this paper, we describe the development of a web-based HTSCS (High Throughput Screening Calculation System), which is the process for assisting high-speed screening and calculation of drug candidates based on biochemical reactions from Nanoluciferase system. This system calculates and displays large amounts of experimental data with single-dose and multi-dose concentration in-vitro cell experiments through charts and graphs. Therefore, we can utilize the HTSCS to save time and effort required for drug screening.