A Survey of Movement Symptom and Quantification Method in Parkinson’s Disease

Daeun Gwon, Yoseop Kim, Sangjun Kim, Myeonghu Song, Minkyu Ahn

http://doi.org/10.5626/JOK.2019.46.4.308

Parkinson’s disease (PD) is a neurodegenerative disease that causes abnormal motor symptoms such as tremor, bradykinesia, stiffness, and postural instability. The number of patients with PD is increasing worldwide. Therefore, it is of great importance to delay the progression of PD through early diagnosis and treatment or to provide appropriate treatment and continuous assistance to PD patients through regular examination to determine changes in their symptoms and the rate of disease progression. In this paper, we investigated motor disease symptoms (tremor, stiffness and bradykinesia) caused by PD and methods that quantified it by engineering. In addition, 67 papers (24 in Korea and 43 abroad) directly related to quantification methods of Parkinsonian motor symptoms were investigated through domestic and international searches of published research papers. As a result of the search, it was confirmed that acceleration / angular velocity (46%) and electromyography (22.7%) were most widely used both in domestic and international research for quantification of movement disorders (tremor, stiffness, bradykinesia) and UPDRS (Unified Parkinson’s Disease Rating Scale) was the most widely used scale (78%, N = 55) to compare and confirm results of such methods.